당뇨병, 골다공증, 갑상선질환, 부신질환, 내분비질환
당뇨병, 골다공증, 갑상선질환, 부신질환, 내분비질환
부산대학교 의과대학 졸업
부산대학교 의과 대학원 석사
부산대학교 의과 대학원 박사
연세대학교 신촌세브란스 내분비내과 전임의
University of Utah, USA Visiting researcher
현, 인제의대 해운대백병원 내분비대사내과 교수
대한당뇨병학회 간행위원, 학술위원, 윤리위원
대한내분비학회 노년내분비연구회 간사
대한당뇨병학회 혈관연구회 간사
대한내분비학회 평의원, 대한당뇨병학회 평의원
부울경내분비학회 총무이사, 감사이사
부산시 항노화산업지원위원회 위원
2016 대한내분비학회 우수연제상
2016 대한내분비학회 우수논문상
2015 대한당뇨병학회 우수논문상
2006 대한 당뇨병 학회 연구비
1999 The 17th Korean Endocrinology Society Meeting, Outstanding Award
Efficacy and safety of evogliptin treatment in patients with type 2 diabetes: A multicentre, active-controlled, randomized, double-blind study with open-label extension (the EVERGREEN study). Diabetes Obes Metab . 2020 Sep;22(9):1527-1536.
Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. Islets. 2020 Jul 16;1-12
The direct effect of lobeglitazone, a new thiazolidinedione, on pancreatic beta cells: A comparison with other thiazolidinediones. Diabetes Res Clin Pract. 2019 May;151:209-223
High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone. J Diabetes Res. 2019 Jan 9;2019:2376512.
Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study. Diabetes Metab J. 2019 Jul 11
The effect of PPARγ agonist on SGLT2 and glucagon expressions in alpha cells under hyperglycemia. J Endocrinol Invest. 2017 Oct;40(10):1069-1076
Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1. Diabetes Res Clin Pract. 2017 Sep;131:1-11
INICOM Study Group. Efficacy and safety of initial combination therapy with gemigliptin and metformin compared with monotherapy with either drug in patients with type 2 diabetes: A double-blind randomized controlled trial (INICOM study). Diabetes Obes Metab. 2017 Jan;19(1):87-97.
Relationship Between Sarcopenia and Albuminuria: The 2011 Korea National Health and Nutrition Examination Survey. Medicine (Baltimore). 2016 Jan;95(3):e2500.
Ginsenoside Rg3 prevents INS-1 cell death from intermittent high glucose stress. Islets. 2016 Apr 18;8(3):57-64.
Repeated Glucose Deprivation/Reperfusion Induced PC-12 Cell Death through the Involvement of FOXO Tranion Factor. Diabetes Metab J. 2016 Oct;40(5):396-405.
The Characteristics of Patients whose both Fasting and Postprandial Glucose were Controlled by Once Daily Basal Insulin Monotherapy. J Diabetes Metab 7:645, 2016.
Relationships of A1c Variability for 10 Years and Beta Cell Function at the Time of Diagnosis in Type 2 Diabetes. Gen Med (Los Angel) 3:177, 2015.
Co-Culture of α TC-6 Cells and β TC-1 Cells: Morphology and Function. Endocrinol Metab 2015;30:92-97.
The effect of proton pump inhibitors on glycated hemoglobin levels in patients with type 2 diabetes mellitus. Can J Diabetes. 2015 Feb;39(1):24-8.
Quantitative Analysis of 3-Dimensional Volumetry and Histogram of Thyroid Gland on Neck Computed Tomography for Patients with Hashimoto's Thyroiditis. J Korean Soc Radiol. 2015 Dec;73(6):367-374.
Assessment of the Association between Mean Hemoglobin A1c Levels for 5 Years and Coronary Artery Disease by Coronary Angiography in Nondiabetic Patients. Diabetes Metab J 2014;38:58-63.
Effect of renin-angiotensin-system blockers on contrast-medium-induced acute kidney injury after coronary angiography. Korean J Intern Med 2014;29:203-209.
Association of low muscle mass and combined low muscle mass and visceral obesity with low cardiorespiratory fitness. PLoS One. 2014 Jun 17;9(6):e100118.
VALUE study group. Efficacy and safety of weekly alendronate plus vitamin D₃ 5600 IU versus weekly alendronate alone in Korean osteoporotic women: 16-week randomized trial. Yonsei Med J. 2014 May;55(3):715-24.
Triiodothyronine induces proliferation of pancreatic β-cells through the MAPK/ERK pathway. Exp Clin Endocrinol Diabetes. 2014 Apr;122(4):240-5.
Serum adipocyte fatty acid-binding protein levels are independently associated with sarcopenic obesity. Diabetes Res Clin Pract. 2013 Aug;101(2):210-7.
A1c variability can predict coronary artery disease in patients with type 2 diabetes with mean a1c levels greater than 7. Endocrinol Metab (Seoul). 2013 Jun;28(2):125-32.
Low glibenclamide concentrations affect endoplasmic reticulum stress in INS-1 cells under glucotoxic or glucolipotoxic conditions. Korean J Intern Med. 2013 May;28(3):339-46.
Increase of INS-1 cell apoptosis under glucose fluctuation and the involvement of FOXO-SIRT pathway. Diabetes Res Clin Pract. 2012 Oct;98(1):132-9.
Prence of echocardiographic criteria for the diagnosis of pulmonary hypertension in patients with Graves disease: before and after antithyroid treatment. Journal of Endocrinological Investigation. 2011, 34: e229-234.
Nateglinide and acarbose for postprandial glucose control after optimizing fasting glucose with insulin glargine in patients with type 2 diabetes. Diabetes Research and Clinical Practice 2011, 322-328.
Influence of Long-term Statin use in Type 2 DiabeticPatients on Thyroid Nodularity in Iodine-sufficient Area. Exp Clin Endocrinol Diabetes 2011; 119: 497?501.
Comparison of EGF with VEGF Non-Viral Gene Therapy for Cutaneous Wound Healing of Streptozotocin Diabetic Mice. Diabetes Metab J, 2011;35;226-235.
Effect of Omega-3 Fatty Acids on Low Density Lipoprotein Subfraction, Adiponectin and Apolipoprotein B in Type 2 Diabetic Patients. EndocrinolMetab26:218-224, 2011
Postprandial lipid levels for assessing target goal achievement in type 2diabetic patients taking statin. J Korean Med Sci. 2010 Mar; 25(3): 387-392.
The effect of chromium on rat insulinoma cells in high glucose conditions. Life Sciences 87 (2010) 401?404.
EGCG and quercetin protected INS-1 cells in oxidative stress via different mechanisms. Front Biosci (Elite Ed). 2010 Jun 1;2:810-7.
The Effect of Glucose Fluctuation on Apoptosis and Function of INS-1 Pancreatic Beta Cells. Korean Diabetes J 2010;34:47-54.
LDL cholesterols levels after statin treatment: A comparison of measured vs. estimated values. Korean J Med 2010 ;79(3):277-284.
Sonoporation of the minicircle-VEGF165 for wound healing of diabetic mice. Pharmaceutical Research, 26(794-801), 2009.
Cause-of-Death Trends for Diabetes Mellitus over 10 Years. Korean Diabetes J. 2009 Feb;33(1):65-72.
The effect of statins on HDL-cholesterol in type 2 diabetic patients. Korean J Med 74:411-417, 2008.
The Protective Effect of EGCG on INS-1 Cell in the Oxidative Stress and Mechanism. Korean Diabetes J. 2008 Apr;32(2):121-130.
Cloning of Novel Epidermal Growth Factor (EGF) Plasmid for Gene Therapy on Diabetic Foot Ulcer. Korean Diabetes J. 2008 Apr;32(2):131-140.
Clinical usefulness of second generation TSH-binding inhibitory immunoglobulin assay using recombinant human TSH receptor in patients with Graves’ disease. J Korean EndocrSoc 23:179-185, 2008.
Comparison of the efficiency and toxicity of sonoporation with branched polyethylenimine-mediated gene transfection in various cultured cell lines. J of Drug Targeting, 16(10): 773-779, 2008.
Cytoprotective Effect by Antioxidant Activity of Quercetin in INS-1 Cell Line. J Korean Diabetes Assoc. 2007 Sep;31(5):383-390.
Comparison of Minicircle with Conventional Plasmid for the Non-viral Vascular Endothelial Growth Factor (VEGF) Gene Therapy. J Korean Diabetes Assoc. 2007 Nov;31(6):465-471.
The effect of Green Tea polyphenol on plasma glucose, lipid levels and antioxidant systems in Type 2 Diabetic patients . J Korean Diabetes Assoc. 2006 May;30(3):217-225.
Prence of Ultrasonographically-Detected Thyroid Nodules in Adults without Previous History of Thyroid Disease. J Kor Endocrino lSoc 21:389~393, 2006.
Evaluation of Glycemic Control in Type 2 Diabetic Patients have been Treated in General Hospital. J Korean Diabetes Assoc. 2004 Jun;28(3):208-218.
The Analysis of BMI of Newly diagnosed Type 2 DM and its Temporal Trends. Korean Journal of Diabetes 27(2):132-140, 2003.
Relationships of Urinary Phyto-oestrogen excretion to BMD in Postmenopausal women. Clinical Endocrinology 56:321-328, 2002. PMID: 11940043
A Study on the Achievement of NCEP-ATP II Goal of Cholesterol Lowering Therapy. Korean Journal of Lipid and Atherosclerosis 11(3):181-189, 2001.
Relationship between Plasminogen Activator Inhibitor-1(PAI-1), Lipoprotein(a) and Diabetic Retinopathy in Type 2 Diabetic Patients. Korean Journal of Diabetes 23(4):552-561,1999.
Clinical Characteristics and Causes of Primary Male Osteoporosis in Korea. Korean Journal of Internal Medicine 57(3): 304-312,1999.